Occurrence and Antibiotic Resistance Profiles of Methicillin-Resistant <i>Staphylococcus Aureus</i> (Mrsa) in Layer Chickens in Kebbi, Nigeria

Abstract Antimicrobial resistance (AMR) is a global health threat, and antimicrobial use in animal production for growth enhancement or prophylaxis contributes to the development of AMR. A cross-sectional study was conducted investigate prevalence methicillin-resistant Staphylococcus aureus (MRSA) poultry farm attendants Kebbi, North-Western Nigeria. total 207 cloacal nasal swabs were randomly collected from four farms comprising 50 samples each only 7 attendants. The analysed using routine bacteriological culture identification techniques. Presumptive MRSA isolates confirmed by PCR assay AMR profiles evaluated Kirby-Bauer disk diffusion method. Of examined, 37.5 % (75/200) layer birds tested positive 71.4 (5/7) positive. All susceptible vancomycin, with an index ˃ 0.3. findings this indicated colonization chickens humans multidrug resistant MRSA, thus highlighting potential role sources transmission multidrug-resistant strains vice versa.